Combined effect of prefrontal transcranial direct current stimulation and a working memory task on heart rate variability.

There were no main fixed effects in the LF band for Group (F (1,20) = 0.487; p = 0.493), Task (F (1,60) = 0.078; p = 0.781), or Period (F (1,60) = 2.708; p = 0.105); however, there was a marginally significant two-way interaction effect between Task and Period (F (1,60) = 4.052; p = 0.049), as well as a non-significant three-way interaction effect (F (1,60) = 3.418; p = 0.069).

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For LF-HRV there was a significant negative correlation with working memory accuracy in the during-tDCS task period (r = -0.50; p = 0.024), however, this association did not quite reach significance in the post-tDCS task period (r = -0.44; p = 0.050) – see Fig 5 .

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