Paracrine Potential of the Human Adipose Tissue-Derived Stem Cells to Modulate Balance between Matrix Metalloproteinases and Their Inhibitors in the Osteoarthritic Cartilage In Vitro.

The low production of soluble VCAM-1, a highly significant risk predictor of hip and knee joint replacement due to severe OA [ 24 ], was determined in supernatants of ASC ( Table 2 ); however, it was abundantly secreted by CE.

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