a statistical trendP = 0.11
In the cohort 2, high SNORA21 expression was also significantly associated with advanced TNM stage and distant metastasis ( P = 0.009 and 0.04, respectively; Table 2 ), while there was a statistical trend observed for lymph node metastasis and vascular invasion ( P = 0.11 and 0.16, respectively; Table 2 ).