Analysis of the ATR-Chk1 and ATM-Chk2 pathways in male breast cancer revealed the prognostic significance of ATR expression.

Finally, in subgroup analysis, pATR expression and the pATR/pChk2 co-expression model were associated with an increased risk of death within a 10-year timeframe in the subgroup of patients with elevated Ki-67 levels and with node-positive disease (Supplementary Figure 1 ), although to a borderline significant extent.

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