Comparing efficacies of moxifloxacin, levofloxacin and gatifloxacin in tuberculosis granulomas using a multi-scale systems pharmacology approach.

if the in vivo C 50 , BI values are significantly higher or lower than the in vitro measured values, the intracellular bacterial population would have a more or less significant role, respectively, in the long-term bacterial response to treatment in our simulations.

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