Mouse strain differences in SSRI sensitivity correlate with serotonin transporter binding and function.

Sci Rep · 2017 · PMC5561191 · PMID 28819255

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may be significantno p-value reported

In conclusion, mouse strain differences in the sensitivity to SSRI treatments were correlated with 5-HT transporter binding and reuptake in these mice, suggesting that the binding and uptake efficiency of the membrane-bound 5-HT transporter may be significant contributing factors to the marked strain differences in immobility time in the TST and FST.

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