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HAF mediates the evasive resistance of anti-angiogenesis TKI through disrupting HIF-1α and HIF-2α balance in renal cell carcinoma.

Oncotarget · 2017 · PMC5564801 · PMID 28572533

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a decreasing trendno p-value reported
an increasing trendno p-value reported
We observed a decreasing trend of HIF-1α protein levels and an increasing trend of HIF-2α and HAF protein levels over the duration of sunitinib treatment (Figure 4E ).

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