highly significantP < 0.001
1B ] in healthy controls (2.8 log IU/L, range: 1.5–4 log IU/L) and HIV-1 infected children (median 1.9 log IU/L, range: 0.1–3.5 log IU/L); the difference between the groups at this time point was also highly significant (P < 0.001).