Role of Neuroinflammation in Amyotrophic Lateral Sclerosis: Cellular Mechanisms and Therapeutic Implications.

Front Immunol · 2017 · PMC5567007 · PMID 28871262

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a positive trendno p-value reported

In the completed phase I and II trials in ALS patients ( ClinicalTrials.gov Identifier: NCT01091142 , NCT01281631 ), NP001 was found to be safe, well tolerated, and presented a positive trend in slowing disease progression ( 120 , 121 ).

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