Susceptible genes and disease mechanisms identified in frontotemporal dementia and frontotemporal dementia with Amyotrophic Lateral Sclerosis by DNA-methylation and GWAS.

Sci Rep · 2017 · PMC5567187 · PMID 28827549

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borderline significanceno p-value reported

Finally, for the pre-defined gene sets we detected borderline significance for the Medial Prefrontal Cortex tissue ( P BH = 0.05).

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borderline significantno p-value reported

In our data set, 12 GRN probes were available for which one probe (cg17101358, located at 5′UTR/1stExon) resulted in borderline significant differences in DNA-methylation levels (P BH = 0.059) in FTD, (compared to the control group with Student T-test).

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