highly significantp < 0.001
The highly significant was labeled as (***) where p < 0.001, more significant (**) where p < 0.01 and significant (*) where p < 0.05 compared with corresponding control group without U0126; (^^^) where p < 0.001, more significant (^^) where p < 0.01 compared with corresponding FSK or DBT group without U0126, respectively.