A systematic review and meta-analysis of the protective effects of metformin in experimental myocardial infarction.

PLoS One · 2017 · PMC5568412 · PMID 28832637

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borderline significantno p-value reported

A borderline significant effect on mortality was observed, and there was no overall effect on cardiac hypertrophy.

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barely significantno p-value reported

Since none of the individual studies showed any effect of metformin on mortality, the pooled effect estimate was barely significant and there was very low heterogeneity in the analysis (I 2 = 0%) an analysis of the influence of cause and timeframe was not deemed feasible.

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