highly significantP < 0.001
somewhat significantP < 0.01
A highly significant ( P < 0.001) increase in the LDH release is observed in groups treated with 10 μg/mL FU-HfO 2 and PEG-HfO 2 with a somewhat significant ( P < 0.01) increase in those treated with 10 μg/mL HfO 2 and 5 μg/mL PEG-HfO 2 .