A comparison of oral controlled-release morphine and oxycodone with transdermal formulations of buprenorphine and fentanyl in the treatment of severe pain in cancer patients.

Drug Des Devel Ther · 2017 · PMC5574595 · PMID 28860712

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highly significantno p-value reported

A highly significant time effect and interactions of treatment time and type of opioid therapy were noted in all items of pain intensity.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.