Switching to Aflibercept in Diabetic Macular Edema Not Responding to Ranibizumab and/or Intravitreal Dexamethasone Implant.

J Ophthalmol · 2017 · PMC5576400 · PMID 28900543

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an overall trendno p-value reported

A more recent retrospective study [ 8 ] on this topic has shown a significant anatomical improvement and an overall trend to functional improvement after switching without reaching significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.