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Hypoxia inducible factor (HIF) as a model for studying inhibition of protein-protein interactions.

Chem Sci · 2017 · PMC5576430 · PMID 28878873

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highly significantno p-value reported
The majority of the review focusses on HIF-1, however a number of highly significant recent articles on HIF-2 are included to highlight the power of various different ligand discovery approaches in modulating HIF biology.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.