A cross-sectional observational study on allergen-specific IgE positivity in a southeast coastal versus a southwest inland region of China.

Among aeroallergens, the prevalence of sIgE positivity for house dust mite showed significant age-group difference only in Guangdong ( X 2 = 104.121, P < 0.001), with an increasing trend between 0–14 years, and peaking at 7–14 years (67.5%).

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In this study, the major allergens for food sensitization in children aged 0–6 years were eggs and milk in both regions, and the prevalence of sIgE positivity for both allergens exhibited a decreasing trend later in life.

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