borderline significantp = 0.055
4a ), also seen as a tendency of increased PI3K signature score (although only borderline significant p = 0.055; Fig. 4c ).
4a ), also seen as a tendency of increased PI3K signature score (although only borderline significant p = 0.055; Fig. 4c ).
S1c ). We employed the PI3K signature score developed by Gustafson 29 , as a measure of PI3K pathway activation, on the set of paired primary and metastatic tumors, and found a tendency of increased PI3K activation in metastases (borderline significance of p = 0.055; Fig. 4c ).