Myeloperoxidase-immunoreactive cells are significantly increased in brain areas affected by neurodegeneration in Parkinson's and Alzheimer's disease.

The number of cells with MPO ir in the frontal cortex was significantly increased in AD cases (means ± SEM 8.46 ± 0.81, n = 25) compared with control cases (5.08 ± 0.62, n = 20), leading to a highly significant difference in the two-tailed t -test ( P = 0.003, t = 3.17, df = 43; Fig. 3 a).

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