Blood Interferon Signatures Putatively Link Lack of Protection Conferred by the RTS,S Recombinant Malaria Vaccine to an Antigen-specific IgE Response.

F1000Res · 2015 · PMC5580375 · PMID 28883910

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highly significantno p-value reported

This is a highly significant landmark but unfortunately the efficacy of the vaccine for unknown reasons, and despite optimization attempts, remains suboptimal 7 , 8 .

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.