Protein tyrosine phosphatase non-receptor 22 and C-Src tyrosine kinase genes are down-regulated in patients with rheumatoid arthritis.

Sci Rep · 2017 · PMC5585411 · PMID 28874816

Europe PMC DOI

hedged sentences

0.0590

closest p · 1.2× alpha

0.0590

boldest claim

The sentences

marginally significantp = 0.059so close (0.05 < p ≤ 0.1)

This decrease in CSK expression was statistically significant in all the cases (p < 0.05), except for individuals who carried CSK rs34933034 risk allele A, that showed a marginally significant decrease (p = 0.059).

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a possible trendno p-value reported

In this regard, whereas a study did not find any polymorphism associated with the expression of PTPN22 splice forms in peripheral blood cells of RA patients 8 , a possible trend for association between PTPN22 rs2488457 SNP and PTPN22 gene expression was described in RA patients from China 12 .

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