An Aggregate Biomarker Risk Score Predicts High Risk of Near-Term Myocardial Infarction and Death: Findings From BARI 2D (Bypass Angioplasty Revascularization Investigation 2 Diabetes).

Discrimination and Calibration Analyses Addition of the BRS to a baseline model consisting of the aforementioned demographic and clinical variables was associated with significant improvements in the c‐statistic for all outcome measures, including all‐cause death (area under the curve [AUC], 0.700–0.715; Δ AUC=0.015; P =0.044), all‐cause death/MI (AUC, 0.634–0.655; Δ AUC=0.021; P =0.002), all‐cause death/MI/revascularization (AUC, 0.574–0.589; Δ AUC=0.015; P =0.015), and for cardiac death (AUC, 0.740–0.760; Δ AUC=0.020; P =0.053) with a trend toward significance.

also in 3,729 other papers