marginally significantP = 0.0574892
Hence, using two-factor repeated-measures ANOVA across time, the lower Mtb load in co-cultured macrophages as well as macrophages co-cultured with LAG-3 silenced blood-derived T-cells, was marginally significant ( P = 0.0574892) relative to infected macrophages ( P <0.01) at 96h ( Fig 3A ).