Association between the functional polymorphism Ile31Phe in the <i>AURKA</i> gene and susceptibility of hepatocellular carcinoma in chronic hepatitis B virus carriers.

Second, although the highly significant association between AURKA Ile31Phe and susceptibility to HCC was derived from a biologically based a priori hypothesis, our initial findings require independent verification in populations with large number of subjects and of different ancestry, with appropriate study design.

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