Intraparenchymal intracranial pressure monitoring for hydrocephalus and cerebrospinal fluid disorders.

The relationship for the Chiari/syrinx and NPH/LOVA cohorts revealed an interesting trend with PA initially rising with ICP (until a median ICP of around 5 mmHg) and then decreasing, revealing perhaps a more complex physiology in these mainly compliance-associated pathologies.

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There was a trend towards significance in the PA for the high-pressure group; it may be hypothesized that this is due to the heterogeneous nature of this diagnostic group, encompassing a number of etiologies (including post-infectious, post-hemorrhagic, and congenital), some of which may be associated with relatively normal intracranial compliance.

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