Loss of SPRR3 in ApoE-/- mice leads to atheroma vulnerability through Akt dependent and independent effects in VSMCs.

PLoS One · 2017 · PMC5590986 · PMID 28886156

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highly significantno p-value reported

Thus, it is highly significant that lesion disruption and early thrombus formation were observed in six out of 24 mouse brachiocephalic arteries in the DKO mice after 6 months HFD.

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