Platelet-Targeted Delivery of Peripheral Blood Mononuclear Cells to the Ischemic Heart Restores Cardiac Function after Ischemia-Reperfusion Injury.

Theranostics · 2017 · PMC5595126 · PMID 28900504

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highly significantno p-value reported

Recent MRI and PET/CT studies using the scFv GPIIb/IIIa , which was used in our study, showed a highly significant accumulation of the targeted antibody to activated platelets within the ischemic myocardium after IR injury, a uniform distribution throughout the ischemic region, as well as occurrence at a well-defined time window peaking 2 hours post reperfusion 20 , 27 .

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