Striking and highly significant differences were found between normal kidney and tumor tissue, with high levels in tumor samples of transcripts of HIF target genes SLC2A1 (encoding Glucose transporter GLUT-1), monocarboxylate transporter SLC16A3 (MCT4), CA9, and LDHA , and low levels of LDHB in contrast to matched normal kidney (Fig. 4e ).
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Profiling of the metabolic transcriptome via single molecule molecular inversion probes.
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