A randomized controlled trial of physical activity with individual goal-setting and volunteer mentors to overcome sedentary lifestyle in older adults at risk of cognitive decline: the INDIGO trial protocol.

These findings would be highly significant as it has been estimated that 13% of all cases of Alzheimer’s disease are potentially attributable to physical inactivity and that a 10–25% reduction of physical inactivity would prevent between 380,000 to 1 million AD cases worldwide [ 76 ].

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