highly significantp < 0.01
The average weight of uteri of pregnant rats treated with 54 mg/kg of imatinib from the 6th to the 13th day of gestation and from the 13th to the 19th day of gestation recorded (16.06 ± 4.36) and (15.28 ± 5.69) respectively, exhibited a highly significant ( p < 0.01, p < 0.001) reduction than those of the control group (35.52 ± 0.70). 3.1.4.2 Average weight of placenta The average weight of placenta exhibited a significant decrease ( p < 0.05) at 36 mg/kg imatinib from the 6th to the 13th recorded (1.0 ± 0.15) and from the 13th to the 19th day of gestation recorded (0.87 ± 0.17) compared to the control group (1.53 ± 0.08).