Cancer stem cells: Role in tumor growth, recurrence, metastasis, and treatment resistance.

Medicine (Baltimore) · 2016 · PMC5599212 · PMID 27611935

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may not be significantno p-value reported

[ 1 , 2 ] CSCs are, however, generally resistant to chemotherapy and radiotherapy, meaning that despite these therapies successfully destroying a large proportion of the tumor bulk, the result may not be significant clinical improvement.

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