Tartrate-resistant acid phosphatase (TRAP/ACP5) promotes metastasis-related properties via TGFβ2/TβR and CD44 in MDA-MB-231 breast cancer cells.

BMC Cancer · 2017 · PMC5602878 · PMID 28915803

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highly significantno p-value reported

Most importantly, we identified a regulation of the TGFβ pathway-associated proteins TGFβ2, TβR1 and SMAD2, as well as a highly significant upregulation of previously unreported phosphorylation sites of CD44 upon TRAP perturbation in the MDA-MB-231 breast cancer cell line.

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