highly significantP -value = 3.22E-11
Highly significant gene ontology (GO) terms were identified for the DPC associated modules including “dendrite morphogenesis” (“blue” module; P -value = 3.22E-11), “negative regulation of synaptic transmission” (“black” module; P -value = 6.29E-09), “negative regulation of axon extension involved in axon guidance” (“red” module; P -value = 3.64E-09) and “embryonic organ morphogenesis” (“green” module, P -value = 1.79E-11), suggesting that the large changes in 5hmC across fetal brain development contribute to the regulation of relevant biological processes.