Furthermore, recent meta-analyses comparing short- versus prolonged-DAPT reported a borderline increase of all-cause death, and highly significant increase of non-cardiac death with prolonged-DAPT.[ 9 – 11 ] However, the DAPT study clearly demonstrated that prolonged-DAPT substantially reduced ischemic events, particularly ST, beyond 1-year after coronary stent implantation.
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Short versus prolonged dual antiplatelet therapy (DAPT) duration after coronary stent implantation: A comparison between the DAPT study and 9 other trials evaluating DAPT duration.
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