The expression of <i>Ldh-c</i> in the skeletal muscle of plateau pika (<i>Ochotona curzoniae</i>) enhances adaptation to a hypoxic environment.

LD content was significantly lower in the siRNA- Ldhc group and S-siRNA- Ldhc group compared with the C, S-C, NS and S-NS groups ( P <0.01); there was a highly significant difference between the resting and swimming states of the plateau pika (C versus S-C, NS versus S-NS, siRNA- Ldhc versus S-siRNA- Ldhc ) ( P <0.01), while there was no significant difference between the C and NS, S-C and S-NS groups ( Fig. 4 C).

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