Characteristic analyses of a neural differentiation model from iPSC-derived neuron according to morphology, physiology, and global gene expression pattern.

Sci Rep · 2017 · PMC5612987 · PMID 28947763

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a decreasing trendno p-value reported

5E , D4 -30 ± 2.3 mV, n = 25; D7 -31.8 ± 2 mV, n = 29; D24 -34.7 ± 2.5 mV, n = 21; D38 -36.8 ± 1.6 mV, n = 26) and membrane resistances showed a decreasing trend (Rm, Fig. 5G , D4 3.05 ± 0.4 GΩ, n = 31; D72.59 ± 0.3 GΩ, n = 32; D24 2.2 ± 0.24 GΩ, n = 25; D38 2.15 ± 0.19 GΩ, n = 26).

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an increasing trendno p-value reported

The area of sEPSC did not increase significantly but showed an increasing trend (Fig. 6D , D4 8.64 ± 3.1 pA*ms, n = 21; D7 21.78 ± 3.91 pA*ms, n = 28; D24 39.99 ± 10.53 pA*ms, n = 25; D38 52.77 ± 25.81 pA*ms, n = 25).

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