STAT3 and NF-κB are common targets for kaempferol-mediated attenuation of COX-2 expression in IL-6-induced macrophages and carrageenan-induced mouse paw edema.

Biochem Biophys Rep · 2017 · PMC5613220 · PMID 28955792

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highly significantno p-value reported

While inhibition of NF-κB p65 phosphorylation was highly significant at a very low concentration of kaempferol (25 μM), phosphorylation of STAT3 was inhibited only at higher concentration of kaempferol at 50 and 100 μM.

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