Transcriptome reprogramming during developmental switching in Physarum polycephalum involves extensive remodeling of intracellular signaling networks.

GATA-, basic-leucine zipper, and myb-like transcription factors along with transcription activators of gluconeogenesis were down-regulated while, among others, nfx1-type zinc finger-containing proteins, the transcriptional regulator cudA , isoforms of the general transcriptional corepressor tupA , and isoforms of the transcription factor Dp-1 were up-regulated in a highly significant manner (Fig. 5 ).

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