The fact that TNF-α was measurable in some dogs before GRID, but became unmeasurable (results below the detection limit) after GRID, is an interesting trend that might account for the initial observed drop in sphingomyelinase activity, though confirmatory studies would certainly be needed to support that hypothesis.
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Outcomes of Spatially Fractionated Radiotherapy (GRID) for Bulky Soft Tissue Sarcomas in a Large Animal Model.
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