highly significantp < 0.0001
Incubating the cells for 24 h with LDC-3 displayed a significant decrease in the PTPIP51/PTP1B complex formation for 0.5 μM and 5 μM LDC-3 (0.5 μM: p < 0.05; 5 μM: p < 0.001) and a highly significant increase of interactions at concentrations from 25 μM to 60 μM being at 25 μM ( p < 0.0001), at 50 μM ( p < 0.001) and at 60 μM ( p < 0.0001) ( Figure 6 ).