Barely Significant
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Class III antiarrhythmic drugs amiodarone and dronedarone impair K<sub>IR</sub> 2.1 backward trafficking.

J Cell Mol Med · 2017 · PMC5618701 · PMID 28425222

Europe PMCDOI
1
hedged sentence
0.2600
closest p · 5.2× alpha
0.2600
boldest claim

The sentences

a slight trendP = 0.26not close (p > 0.1)
Chronic dronedarone treatment resulted in a slight trend towards increased I KIR2.1 densities for the inward (43.8 ± 5.5%, P = 0.26 at −120 mV) and a non‐significant increase in outward (32.0 ± 7.8%, P = 0.83 at −60 mV) current components. 24‐hrs treatment with amiodarone resulted in a significant increase in the inward current component at −120, −110 and −100 mV of 73.3 ± 10.3%, 78.0 ± 10.9% and 84.4 ± 11.5%, respectively, whereas a non‐significant increased outward current (75.9 ± 24.9%, P = 0.38 at −60 mV) was observed.

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