We found a markedly significant reduce in mortality in critically ill patients assigned to early RRT in the CRRT group (OR, 0.40; 95% CI, 0.30 - 0.54; I 2 , 28.4%), IHD group (OR, 0.11; 95% CI, 0.03 - 0.43; I 2 , 56.9%) and Mixed group (OR, 0.45; 95% CI, 0.35 - 0.57; I 2 , 53.6%) when compared to late RRT.
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The optimal time of initiation of renal replacement therapy in acute kidney injury: A meta-analysis.
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