Amotosalen/ultraviolet A pathogen inactivation technology reduces platelet activatability, induces apoptosis and accelerates clearance.

The platelet-covered area from IBS samples showed a 47% reduction in collagen compared to non-IBS (from 38′561 μm 2 to 20′718 μm 2 , n=17; Figure 1E ), and a 65% reduction on vWF (from 2490 μm 2 to 866 μm 2 , n=17; Figure 1F ), which reached a borderline significance for the area under the curve (AUC) for collagen ( P =0.05; Figure 1G ), and was significant for vWF ( P =0.01; Figure 1H ).

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