Loss-of-function but not dominant-negative intragenic <i>IKZF1</i> deletions are associated with an adverse prognosis in adult <i>BCR-ABL</i>-negative acute lymphoblastic leukemia.

Haematologica · 2017 · PMC5622858 · PMID 28751559

Europe PMC DOI

hedged sentence

0.0600

closest p · 1.2× alpha

0.0600

boldest claim

The sentences

narrowly missed statistical significanceP =0.06so close (0.05 < p ≤ 0.1)

0.68; P =0.0002), while in high-risk patients, the trend towards inferior OS narrowly missed statistical significance (0.26 vs. 0.46; P =0.06).

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