In addition, three T-cell receptor (TCR)-related pathways (TCR -> NF-kB, TCR -> CREBBP and TCR -> NFATC) consisting of CD4, CD8A, CD8B, CD22, CD28, CD72, CD80, CD86, NFKBIA, VAV1, LYN, PTPRC, SYK, PLCG1, PRKCQ, FYN, BCL10, ITK, PTPN6, CARD11, CTLA4, IL16, MAP3K7, LAT, PDCD1, LCK, BTK, ZAP70, MALT1, TRAF6, LCP2, PLCG2, ITPR1, CAMK4, CREBBP, CAMKK2, CAMKK1, NFAT5, NFATC4, NFATC3, NFATC1 and NFATC2 molecules were highly significant at both early (7d and 1M) and late (15M and 18M) time points.
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Gene expression profiling of hepatocarcinogenesis in a mouse model of chronic hepatitis B.
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