highly significantP = 3.60 × 10 −203
Fewer TEs are derepressed in smc4-1 (286) than in met1 (956), but 63% (181 of 286) of these SMC4 -dependent TEs overlap with TEs derepressed in met1 , which is highly significant ( P = 3.60 × 10 −203 ) given an expectation of only 3.1% overlap by chance.