An atlas of alternative splicing profiles and functional associations reveals new regulatory programs and genes that simultaneously express multiple major isoforms.

Interestingly, investigation of intragenic relationships between VastDB AS events reveals that pairs of cassette exons (especially in the case of neighboring exons) and pairs of retained introns within the same gene show highly significant correlation of inclusion or retention levels across samples from each species ( P < 10 −5 , Wilcoxon rank-sum test) ( Supplemental Fig.

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