The Molecular Chaperone DnaK Is a Source of Mutational Robustness.

We find a strong and highly significant positive association between DnaK dependency and the rate of nonsynonymous substitutions for S. enterica and E. coli (Spearman’s rank correlation coefficient, ρ = 0.367, N = 627, P < 2.2 × 10 − 16 ; fig. 4A ).

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