Association of fatty acid-binding protein 2 and fat mass and obesity-associated gene polymorphism with primary open-angle glaucoma.

Indeed, the POAG patients studied had reduced total omega-3 long-chain polyunsaturated fatty acids, eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA) fatty acids.[ 7 ] These findings may be significant as EPA and DHA could modulate impaired systemic microcirculation, ocular blood flow, and positively impact optic neuropathy, which are the main physiological changes associated with glaucoma.[ 21 ] Numerous studies have assessed FABP2 gene variants and their association with insulin resistance and type 2 diabetes mellitus.[ 7 ] This is the first time we are reporting this gene polymorphism in POAG cases.

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