At multivariable analysis adjusted for other potential confounding factors, statin use (OR, 0.51; 95% CI, 0.32–0.80) was associated to a reduced risk of PDAC occurrence, while the association for aspirin use was of borderline significance (OR, 0.64; 95% CI, 0.40–1.01).
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Exclusive and Combined Use of Statins and Aspirin and the Risk of Pancreatic Cancer: a Case-Control Study.
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Overall use of aspirin and statins and risk of pancreatic cancer Seventy-eight cases (19.1%) and 191 controls (23.4%) reported ever use of aspirin, which was associated with a statistically borderline significant reduced PDAC risk (age- and sex-adjusted OR, 0.74; 95% CI, 0.54–1.02; Table 2 ).